Comprehensive Neuropathies Panel Test code: 03200 • 10–21 days turnaround time
est Description
The Fact DNA Comprehensive Neuropathies Panel evaluates a broad range of genes associated with hereditary neuropathies, including Charcot-Marie-Tooth disease (CMT), hereditary motor neuropathy (HMN), and hereditary sensory and autonomic neuropathy (HSAN).
Hereditary neuropathies can have overlapping symptoms and may result from changes in many different genes. Because clinical symptoms alone may not identify the underlying genetic cause, comprehensive genetic testing can provide an efficient way to evaluate multiple potential genetic contributors through a single testing approach.
The genes included in this panel are selected based on available scientific and clinical evidence regarding hereditary neuropathies. Some genes evaluated may also be associated with other medical conditions that are outside the scope of this particular test.
Potential Benefits of Genetic Testing
Genetic testing may provide information that can help healthcare professionals:
- Support or clarify a suspected diagnosis
- Identify a potential genetic cause of neuropathy
- Provide information that may assist in understanding disease course
- Support appropriate medical evaluation and monitoring
- Help inform treatment and care considerations
- Identify potential risks for other family members
- Support family planning and genetic counseling
- Determine whether additional relatives may benefit from genetic evaluation
- Identify potential opportunities for participation in certain research studies or clinical trials
Who May Consider Testing?
This panel may be considered for individuals experiencing symptoms or clinical findings suggestive of a hereditary neuropathy, including unexplained peripheral neuropathy, muscle weakness, sensory changes, or a family history of inherited neurological conditions.
A qualified healthcare professional can determine whether genetic testing is appropriate based on the individual's symptoms, medical history, and family history.
Genetic testing does not identify the cause of every neuropathy and does not guarantee a definitive diagnosis. Results should be interpreted by a qualified healthcare professional or genetic counselor in conjunction with the patient's clinical and family history.