Primary Immunodeficiency Panel Test code: 08100 • Up to 474 genes
Primary Immunodeficiency Panel
This panel analyzes genes associated with inherited disorders of the immune system, collectively known as primary immunodeficiencies (PIDs) or inborn errors of immunity.
Primary immunodeficiencies can affect the body's ability to recognize and respond to infections and may vary widely in their clinical presentation, severity, and age of onset. Because these disorders can have overlapping features and multiple genetic causes, comprehensive genetic testing can provide an efficient evaluation of numerous potential conditions based on a single clinical indication.
The panel includes genes selected based on current available evidence and is designed to provide a broad evaluation of genetic causes of primary immunodeficiency and related immune system disorders.
Genetic testing may help:
- Identify an underlying genetic cause of immune dysfunction
- Confirm or clarify a suspected diagnosis
- Distinguish between different inherited immune disorders
- Guide medical management and treatment decisions
- Support appropriate monitoring and surveillance
- Help assess potential risks for infections and other complications
- Inform family planning and genetic counseling
- Identify potentially affected relatives who may benefit from genetic testing
Genetic test results should be interpreted in conjunction with the individual's medical history, infection history, immune system evaluations, laboratory findings, and family history to support an appropriate diagnosis and management plan.