Hereditary Gastric Cancer Panel Test code: 01271 • 21 genes

Hereditary Gastric Cancer Panel                    21 genes

This panel analyzes genes associated with an inherited predisposition to stomach (gastric) cancer. It is designed to evaluate multiple genetic causes of hereditary gastric cancer and provide information that may help guide clinical assessment, cancer surveillance, and family risk evaluation.

Because hereditary gastric cancer conditions can have overlapping clinical features, it may be difficult to determine the underlying genetic cause based solely on an individual's personal or family history. Broad panel testing allows for an efficient evaluation of multiple potential genes based on a single clinical indication.

Genetic testing may provide valuable information by helping to:

• Confirm or clarify a clinical diagnosis

• Identify an inherited predisposition to gastric cancer

• Assess hereditary cancer risk

• Support appropriate cancer screening and surveillance

• Help facilitate earlier detection of cancer or related symptoms

• Inform family planning and genetic counseling

• Identify potentially affected relatives who may benefit from genetic testing

• Help assess disease prognosis and progression when applicable

• Support consideration for relevant clinical trials

Some genes included in this panel may also be associated with additional medical conditions unrelated to hereditary gastric cancer. These conditions are not included among the disorders specifically evaluated by this test.

Important Testing Information:
This panel is specifically designed to identify heritable germline genetic variants. It is not intended to detect somatic mutations in tumor tissue and should not be used as a substitute for tumor-based somatic testing.