Familial Hypercholesterolemia Panel Test code: 02401 • 10–21 days turnaround time 4 genes
Familial Hypercholesterolemia (FH) Panel
This panel provides a comprehensive genetic analysis of genes associated with familial hypercholesterolemia (FH), an inherited condition characterized by abnormally elevated cholesterol levels and an increased risk of premature cardiovascular disease.
Individuals with unexplained elevated cholesterol levels or a personal or family history of early cardiovascular disease may benefit from genetic testing to help confirm or clarify an FH diagnosis.
Identifying a genetic cause may help healthcare professionals:
- Confirm or clarify a diagnosis of familial hypercholesterolemia
- Assess inherited cardiovascular risk
- Guide appropriate medical management and preventive strategies
- Support more targeted treatment decisions
- Reduce the risk of cardiovascular events through early intervention
- Identify family members who may have inherited the condition
- Support genetic counseling and family testing
- Enable at-risk relatives to receive appropriate monitoring and preventive treatment
Early identification and appropriate medical intervention may significantly reduce the risk of cardiovascular complications associated with FH. Identifying affected relatives can also allow preventive measures and treatment to be initiated before serious cardiovascular disease develops.
Clinical Evidence:
The Centers for Disease Control and Prevention (CDC) Office of Public Health Genomics has categorized genetic testing for familial hypercholesterolemia as a Tier 1 genomic application, indicating that there is evidence supporting the use of this type of genetic testing in clinical practice.
Genetic test results should be interpreted in conjunction with the individual's cholesterol levels, medical history, family history, and other cardiovascular risk factors.