Hereditary Colorectal Cancer Guidelines-Based Panel up to 22 genes

Hereditary Colorectal Cancer Guidelines-Based Panel up to 22 genes
$0.00

Hereditary Colorectal Cancer Guidelines-Based Panel       up to 22 genes

This panel analyzes genes associated with hereditary predisposition to colorectal polyps and colorectal cancer for which medically actionable, published, evidence-based screening, management, and risk-reduction strategies are available.

Individuals with a hereditary predisposition to colorectal cancer may require specialized and, in some cases, intensive medical management. Genetic testing can help guide personalized colorectal cancer screening and risk-reduction strategies, including:

  • Determining the appropriate age to begin colorectal cancer screening

  • Establishing the recommended frequency and intervals between screenings

  • Identifying appropriate screening methods

  • Evaluating preventive and risk-reduction options, including surgery

  • Assessing the potential risk of developing additional primary cancers

  • Supporting earlier detection and intervention when appropriate

These strategies may help prevent cancer, reduce cancer risk, or facilitate earlier diagnosis, potentially improving treatment options and the likelihood of successful outcomes.

Because hereditary colorectal cancer conditions can have significant clinical overlap, broad panel testing allows for an efficient evaluation of multiple potential genes based on a single clinical indication. Some genes included in the panel may also be associated with additional medical conditions unrelated to hereditary colorectal cancer or colorectal polyposis. These additional conditions are not included among the disorders specifically evaluated by this test.

Genetic testing may provide additional clinical value by helping to:

  • Confirm or clarify a clinical diagnosis

  • Identify an underlying hereditary cancer predisposition

  • Assess colorectal cancer and polyp risk

  • Guide personalized screening and risk-reduction strategies

  • Help predict disease prognosis and progression

  • Support earlier detection and appropriate surveillance

  • Inform family planning and genetic counseling

  • Identify potentially affected relatives who may benefit from genetic testing

  • Support consideration for relevant clinical trials

Important Testing Information:
This panel is specifically designed to identify heritable germline genetic variants. It is not intended to detect somatic mutations in tumor tissue and should not be used as a substitute for tumor-based somatic testing.