BRCA1 and BRCA2 Genetic STAT Panel

BRCA1 and BRCA2 Genetic Testing.                    2 genes

This test analyzes the BRCA1 and BRCA2 genes, which are strongly associated with adult-onset hereditary breast and ovarian cancer syndrome (HBOC) and an increased risk for certain hereditary cancers.

Genetic testing may provide important information for individuals who have been diagnosed with breast cancer or who may have an increased hereditary risk. Identification of a pathogenic or likely pathogenic variant may indicate an increased risk of developing another breast cancer or other BRCA-associated cancers. These results may help patients and their physicians make informed decisions regarding surgical options, cancer treatment, surveillance, and ongoing medical management.

Because genetic results may influence time-sensitive treatment or surgical decisions, accelerated turnaround time (TAT) may be beneficial when rapid clinical decision-making is needed.

BRCA1 and BRCA2 have well-established medical management and risk-reduction guidelines. Identification of a disease-causing variant may also provide valuable information for genetic counseling and cascade testing of at-risk relatives, allowing family members to better understand their potential hereditary cancer risk and consider appropriate screening or preventive measures.

Important Testing Information:
This test is specifically designed to identify heritable germline genetic variants in the BRCA1 and BRCA2 genes. It is not intended to detect somatic mutations in tumor tissue and should not be used as a substitute for tumor-based somatic testing.